Survival benefits of adjuvant chemotherapy after conversion surgery in patients with advanced pancreatic cancer.

ABSTRACT:

Background

Oncologic outcomes of conversion surgery for advanced pancreatic cancer (PC) have scarcely been reported. Therefore, this study aimed to investigate the outcomes of conversion surgery with preoperative treatment of FOLFIRINOX or gemcitabine with nab-paclitaxel (GnP) for patients with advanced PC including locally advanced or metastatic PC.

Methods

Using the National Health Insurance database between 2005 and 2020, we identified patients who underwent conversion surgery after chemotherapy with FOLFIRINOX or GnP for advanced PC. The patients were categorized based on preoperative treatment. Survival outcomes were evaluated based on the date of cancer diagnosis and conversion surgery.

Results

Among 69,183 patients with advanced PC, 476 underwent conversion sur

SUBMITTER: Lee YS 

PROVIDER: S-EPMC11746061 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature