Increased risk of type 2 diabetes after traumatic amputation: a nationwide retrospective cohort study.

ABSTRACT:

Background

Amputation confers disabilities upon patients and is linked to cardiometabolic morbidity and mortality. We aimed to compare the incidence of type 2 diabetes (T2DM) between individuals following amputation with those of the general population.

Methods

We performed a population-based retrospective cohort study using the Nationwide Health Insurance Service database. A total of 21,343 individuals with amputation during 2010-2018 and their 1:3 age- and sex-matched controls was included. We conducted Cox proportional hazard analysis to calculate the risk of T2DM among individuals with amputation.

Results

During the 4.2 ± 2.5 year mean follow-up period, there were 912 incident T2DM cases (10.7 per 1,000 person-years) among individuals with amputation. Individuals

SUBMITTER: Yoo JE 

PROVIDER: S-EPMC11746081 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature