Statins and the incidence of post-stroke depression: a systematic review and meta-analysis.

ABSTRACT:

Introduction

Post-stroke depression (PSD) can lead to poorer functional outcomes and prognosis. Brain inflammation is a risk factor for PSD. Statins might be beneficial due to their anti-inflammatory properties. Different studies have yielded varying results regarding the effects of statins. Therefore, this meta-analysis aims to clarify the effect of statins on PSD.

Methods

Objectives: To evaluate the relationship between PSD and the use of statins. Data Sources: Databases including PubMed, Web of Science, Embase, and Cochrane Library. Eligibility Criteria: Original observational cohort studies. Participants: Patients with ischemic stroke. Interventions: Use of statins. Appraisal and Synthesis Methods: Forest plot to display pooled results; I ² test to eval

SUBMITTER: Cui C 

PROVIDER: S-EPMC11746108 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature