Kidney volume and function of low-birth-weight children at 5 years: impact of singleton and twin birth.

ABSTRACT:

Background

Many studies have demonstrated the association between low birth weight (LBW) and chronic kidney disease, estimated glomerular filtration rate (eGFR) and kidney volume (KV). However, studies on twins and those investigating numerous perinatal factors beyond LBW, and their associations with various kidney parameters are scarce.

Methods

A two-center cross-sectional study on five-year-old LBW children was conducted between 2021 and 2023. 110 children were enrolled (8 LBW, 58 very LBW (VLBW), 44 extremely LBW (ELBW)); 56 were twins. We examined associations between birth weight (BW), various prenatal, perinatal and postnatal factors, and eGFR, KV, tubular abnormalities and kidney ultrasound abnormalities, both in singletons and twins.

Results

In children with E

SUBMITTER: Konopasek P 

PROVIDER: S-EPMC11746971 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature