Effect of H₂O₂ induced oxidative stress on volatile organic compounds in differentiated 3T3-L1 cells.

ABSTRACT: Oxidative stress (OS) refers to the disruption in the balance between free radical generation and antioxidant defenses, leading to potential tissue damage. Reactive oxygen species (ROS) can interact with biological components, triggering processes like protein oxidation, lipid peroxidation, or DNA damage, resulting in the generation of several volatile organic compounds (VOCs). Recently, VOCs provided new insight into cellular metabolism and can serve as potential biomarkers. The objective is to investigate the impact of OS on cell metabolism by analyzing the release or alterations of VOCs in the headspace of differentiated 3T3-L1 adipocytes. An OS model in differentiated 3T3-L1 cell lines was constructed using hydrogen peroxide (H₂O₂) treatment. The effect of OS on c

SUBMITTER: Oyerinde AS 

PROVIDER: S-EPMC11747074 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature