Nomogram models for predicting outcomes in thyroid cancer patients with distant metastasis receiving ¹³¹iodine therapy.

ABSTRACT: This study aimed to establish and validate prognostic nomogram models for patients who underwent ¹³¹I therapy for thyroid cancer with distant metastases. The cohort was divided into training (70%) and validation (30%) sets for nomogram development. Univariate and multivariate Cox regression analyses were used to identify independent predictors for overall survival (OS) and progression-free survival (PFS). Nomograms were developed based on these predictors, and Kaplan-Meier curves were constructed for validation. Among 451 patients who were screened, 412 met the inclusion criteria and were followed-up for a median duration of 65.2 months. The training and validation sets included 288 and 124 patients, respectively. Pathological type, first ¹³¹I administrated activity,

SUBMITTER: Jin S 

PROVIDER: S-EPMC11747094 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature