Contrasting vector competence of three main East African Anopheles malaria vector mosquitoes for Plasmodium falciparum.

ABSTRACT: There are three Anopheles mosquito species in East Africa that are responsible for the majority of malaria transmission, posing a significant public health concern. Understanding the vector competence of different mosquito species is crucial for targeted and cost-effective malaria control strategies. This study investigated the vector competence of laboratory reared strains of East African An. gambiae sensu stricto, An. funestus s.s., and An. arabiensis mosquitoes towards local isolates of Plasmodium falciparum infection. Mosquito feeding assays using gametocytaemic blood from local donors revealed significant differences in both prevalence and intensity of oocyst and sporozoite infections among the three vectors. An. funestus mosquitoes presented the highest sporozoite prevalence 23.5% (9

SUBMITTER: Kweyamba PA 

PROVIDER: S-EPMC11747171 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature