Maternal diet in pregnancy and the risk of inflammatory bowel disease in the offspring: a prospective cohort study.

ABSTRACT:

Background

Diet has been hypothesized as a risk factor for the development of inflammatory bowel disease (IBD).

Objective

The objective of this study was to explore associations between maternal diet diversity and quality in pregnancy and the offspring's risk of IBD.

Methods

We used data from a nationwide cohort study on 85,129 Norwegian children followed from birth (1999-2009) with information on maternal diet in pregnancy from validated food frequency questionnaires. Hazard ratios (HRs) for IBD, Crohn disease (CD), and ulcerative colitis (UC) by maternal diet diversity, quality, and intake amounts of individual food groups were adjusted for maternal BMI, parental IBD, and sociodemographic factors. Sensitivity analyses were adjusted for the child's early-life diet qu

SUBMITTER: Guo A 

PROVIDER: S-EPMC11747187 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature