Human milk feeding practices and serum immune profiles of one-year-old infants in the CHILD birth cohort study.

ABSTRACT:

Background

Breastfeeding and human milk consumption are associated with immune system development; however, the underlying mechanisms and the impact of different infant feeding practices are unclear.

Objectives

This study aimed to investigate how current human milk feeding (HMF) status is related to infant immune biomarker profiles, as well as explore relationships with HMF history (i.e., duration, exclusivity, and method: directly from the breast or pumped and bottled).

Methods

This observational birth cohort study involved 605 infants from the Canadian CHILD Cohort Study. Infant feeding was captured from hospital birth records and parent questionnaires. Ninety-two biomarkers reflecting immune system activity and development were measured in serum collected at 1 y (1

SUBMITTER: Ames SR 

PROVIDER: S-EPMC11747196 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature