Associations between dietary fibers and gut microbiome composition in the EDIA longitudinal infant cohort.

ABSTRACT:

Background

The infant gut microbiome undergoes rapid changes in the first year of life, supporting normal development and long-term health. Although diet shapes this process, the role of fibers in complementary foods on gut microbiome maturation is poorly understood.

Objectives

We explored how the transition from human milk to fibers in complementary foods shapes the taxonomic and functional maturation of the gut microbiome within the first year of life.

Methods

We assessed the longitudinal and cross-sectional development of infant gut microbiomes (N = 68 infants) and metabolomes (N = 33 infants) using linear mixed models to uncover their associations to dietary fibers and their food sources. Fiber intakes were assessed with 3-d food records (months 3, 6, 9, and 12) r

SUBMITTER: Lalli MK 

PROVIDER: S-EPMC11747200 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature