A rapid literature review of the impact of penicillin allergy on antibiotic resistance.

ABSTRACT:

Background

Antimicrobial resistance (AMR) is caused by the use and misuse of antibiotics. AMR is a global health concern, to which penicillin allergy (penA) labels appear to contribute. Patients who have penA labels are treated with non-penicillin antibiotics and receive more antibiotics when compared with patients without penA. Although penA is common, after formal allergy assessments, >90% of people with a penA label are found not to be allergic; therefore, broad-spectrum antibiotics are being misused and overused unnecessarily in these patients. Antimicrobial stewardship policies now advocate assessment to identify and remove incorrect penA labels; however, there is limited evidence on whether rectifying incorrect penA labels results in less AMR. This review aimed to assess the

SUBMITTER: Ahmed S 

PROVIDER: S-EPMC11747217 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature