Maternal exposure to dim light at night induces behavioral alterations in the adolescent and adult offspring Wistar rat.

ABSTRACT:

Introduction

Access to electric light has exposed living organisms to varying intensities of light throughout the 24 h day. Dim light at night (DLAN) is an inappropriate signal for the biological clock, which is responsible for the circadian organization of physiology. During the gestational period, physiological adaptations occur to ensure a successful pregnancy and optimal fetal development. Environmental maternal conditions, such as disruptions of maternal circadian rhythms, could negatively affect offspring health. We have previously demonstrated that exposure of female Wistar rats to DLAN results in circadian, metabolic, and behavioral alterations. A relevant behavior during adolescence is social play, primarily regulated by the nucleus accumbens (NAc) which is crucial for the

SUBMITTER: Gonzalez-Gonzalez S 

PROVIDER: S-EPMC11747224 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature