Impact of protein intake from a caloric-restricted diet on liver lipid metabolism in overweight and obese rats of different sexes.

ABSTRACT: In addition to being linked to an excess of lipid accumulation in the liver, being overweight or obese can also result in disorders of lipid metabolism. There is limited understanding regarding whether different levels of protein intake within an energy-restricted diet affect liver lipid metabolism in overweight and obese rats and whether these effects differ by gender, despite the fact that both high protein intake and calorie restriction can improve intrahepatic lipid. The purpose of this study is to explore the effects and mechanisms of different protein intakes within a calorie-restricted diet on liver lipid metabolism, and to investigate whether these effects exhibit gender differences. The Sprague-Dawley rats, which were half female and half male, were used to construct a rat model o

SUBMITTER: Tian Y 

PROVIDER: S-EPMC11747403 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature