Transdiagnostic modeling of clinician-rated symptoms in affective and nonaffective psychotic disorders.

ABSTRACT: Prevailing factor models of psychosis are centered on schizophrenia-related disorders defined by the Diagnostic and Statistical Manual of Mental Disorders and International Classification of Diseases, restricting generalizability to other clinical presentations featuring psychosis, even though affective psychoses are more common. This study aims to bridge this gap by conducting exploratory and confirmatory factor analyses, utilizing clinical ratings collected from patients with either affective or nonaffective psychoses (n = 1,042). Drawing from established clinical instruments, such as the Positive and Negative Syndrome Scale, Young Mania Rating Scale, and Montgomery-Åsberg Depression Rating Scale, a broad spectrum of core psychotic symptoms was considered for the mod

SUBMITTER: Chung Y 

PROVIDER: S-EPMC11747831 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature