A Pilot Study of the Gut Microbiota in Spine Fusion Surgery Patients.

ABSTRACT:

Background

The microbiome has been identified as a contributor to bone quality. As skeletal health is critical to success of orthopedic surgery, the gut microbiome may be a modifiable factor associated with postoperative outcomes. For spine fusion surgery in particular, de novo bone formation and sufficient bone mineral density are essential for successful outcomes. Given the prevalence and complexity of these procedures, the identification of novel factors that may be related to operative success is important.

Questions/purposes

We sought to investigate how the composition of the microbiota related to bone health in a focused spinal fusion surgery cohort.

Methods

We investigated the composition of the microbiome in a cohort of 31 patients prior to spinal fusio

SUBMITTER: Cyphert EL 

PROVIDER: S-EPMC11748416 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature