The prebiotic potential of dietary onion extracts: shaping gut microbial structures and promoting beneficial metabolites.

ABSTRACT: Onions are well-known vegetables that offer various health benefits. This study explores the impact of onion extracts on gut microbiome using an in vitro fecal incubation model and metabolome analysis. Fecal samples were collected from 19 healthy donors and incubated in the presence or absence of onion extracts for 24 h. To reduce inter-individual variability in the gut microbiome, we employed enterotyping based on baseline fecal microbiota: 14 subjects with a Bacteroides-dominant type (enterotype B) and 5 subjects with Prevotella-dominant type (enterotype P). Alpha diversity was significantly reduced in the onion-treated group compared to the non-treated control group in both Bacteroides- and Prevotella-dominant types. However, significant structural dif

SUBMITTER: Yoo Y 

PROVIDER: S-EPMC11748487 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature