Efficacy and safety of molecular targeted therapies in nasopharyngeal carcinoma: a network meta-analysis.

ABSTRACT:

Background

Nasopharyngeal carcinoma (NPC) is one of the most common head and neck cancers worldwide. The majority of the new cases were from Asia and are the leading cause of cancer in China. The main treatment is surgery and radiotherapy with chemotherapy for advanced cases. With the advancement of targeted therapies, the objective of this study was to investigate the efficacy and safety of targeted therapies in NPC.

Methods

Databases were searched from inception to Aug 2023, comparing molecular targeted therapies (MTT) with conventional chemotherapy, chemotherapy or surgery. Study screening, data extraction, and data analysis were conducted independently by two investigators. The Cochrane Risk of Bias tool 1.0 was used for the quality of the studies.

Results

There w

SUBMITTER: Htet H 

PROVIDER: S-EPMC11748561 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature