Understanding variation in management of early-onset neonatal sepsis in India: a vignette-based survey.

ABSTRACT:

Background

Antibiotic use for early-onset neonatal sepsis (EONS) is common, but prolonged exposure can lead to poor outcomes. Laboratory capacity and infection prevention initiatives may impact antibiotic use for EONS in neonatal intensive care units. The objective of this study was to examine the influence of institutional capacity on antibiotic prescribing for EONS in India.

Methods

Between September 2023 and January 2024, we surveyed Indian paediatricians and neonatologists regarding institutional capacity and antibiotic prescribing practices for EONS. Five vignettes with varying maternal and infant risk profiles explored participants' decision to initiate empiric antibiotics at birth and the timing of discontinuation of antibiotics in term and preterm infants at risk for

SUBMITTER: McAleese S 

PROVIDER: S-EPMC11748779 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature