Impact of Bifurcation Lesions on Outcomes After FFR-Guided PCI or CABG.

ABSTRACT:

Background

In the era of first-generation drug-eluting stents and angiography-guided percutaneous coronary intervention (PCI), the presence of a bifurcation lesion was associated with adverse outcomes after PCI. In contrast, the presence of a bifurcation lesion had no impact on outcomes following coronary artery bypass grafting (CABG). Therefore, the presence of a coronary bifurcation lesion requires special attention when choosing between CABG and PCI. The aim of this study is to assess whether the presence of a bifurcation lesion still influences clinical outcomes after contemporary PCI using second-generation drug-eluting stent and fractional flow reserve (FFR) guidance versus CABG.

Methods

The randomized FAME 3 trial (Fractional Flow Reserve Versus Angiography for Multiv

SUBMITTER: Dillen DMM 

PROVIDER: S-EPMC11748902 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature