Validation of the Valve Academic Research Consortium High Bleeding Risk Definition in Patients Undergoing TAVR.

ABSTRACT:

Background

The Valve Academic Research Consortium for High Bleeding Risk (VARC-HBR) has recently introduced a consensus document that outlines risk factors to identify high bleeding risk in patients undergoing transcatheter aortic valve replacement. The objective of the present study was to evaluate the prevalence and predictive value of the VARC-HBR definition in a contemporary, large-scale transcatheter aortic valve replacement population.

Methods

Multicenter study including 10 449 patients undergoing transcatheter aortic valve replacement. Based on consensus, 21 clinical and laboratory criteria were identified and classified as major or minor. Patients were stratified as at low, moderate, high, and very high bleeding risk according to the VARC-HBR definition. The primary

SUBMITTER: Avvedimento M 

PROVIDER: S-EPMC11748903 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature