Efficacy of esketamine for chronic post-thoracotomy pain: protocol for a systematic review and meta-analysis.

ABSTRACT:

Introduction

Chronic post-thoracotomy pain (CPTP) is a persistent and disabling condition affecting a significant proportion of patients after thoracotomy and posing a challenge for clinicians, despite advances in surgical and pain management strategies. Esketamine, the S-enantiomer of ketamine, has emerged as a promising therapeutic agent for various pain conditions, with evidence for its effectiveness in alleviating acute and chronic pain. This systematic review and meta-analysis will be conducted to assess the efficacy of esketamine in treating CPTP, and evaluate its effectiveness in reducing pain intensity, improving functional outcomes, and reducing opioid consumption, as well as its adverse effects.

Methods and analysis

Computer-based literature retrieval in the PubMed

SUBMITTER: Juan S 

PROVIDER: S-EPMC11749034 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature