Age-dependent effect of vitamin D supplementation on musculoskeletal health in chronic spinal cord injury patients: A pilot study.

ABSTRACT:

Objective

To determine the effect of vitamin D supplementation on changes in body composition associated with musculoskeletal health status in patients with chronic SCI and vitamin D deficiency as a response to age.

Design

Prospective drug-intervention study.

Setting

Department of rehabilitation medicine, Veterans Health Service Medical Center.

Participants

Seventeen patients with vitamin D insufficiency/deficiency (<30 ng/mL) and chronic SCI were divided into two groups: groups A <65 years (n = 8) and B ≥65 years of age (n = 9).

Interventions

Both groups received 800 IU/day cholecalciferol for 12 weeks.

Outcome measures

We used blood samples to evaluate metabolites related to vitamin D, testosterone (T), lipid profiles, and sex horm

SUBMITTER: Yang HE 

PROVIDER: S-EPMC11749134 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature