Heart failure subphenotypes based on mean arterial pressure trajectory identify patients at increased risk of acute kidney injury.

ABSTRACT:

Background

Acute kidney injury (AKI) is a common complication in heart failure (HF) patients. Patients with heart failure who experience renal injury tend to have a poor prognosis. The objective of this study is to examine the correlation between the occurrence of AKI in heart failure patients and different mean arterial pressure (MAP) trajectories, with the goal of improving early identification and intervention for AKI.

Methods

A retrospective study was conducted on patients with heart failure using data from the Medical Information Mart for Intensive Care IV (MIMIC-IV). We utilized the group-based trajectory modeling (GBTM) method to classify the 24-hour MAP change trajectories in heart failure patients. The occurrence of AKI within the first 7 days of intensive care unit

SUBMITTER: Wang X 

PROVIDER: S-EPMC11749146 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature