A new epidemic wave of Bordetella pertussis in paediatric population: impact and role of co-infections in pertussis disease.

ABSTRACT:

Background

In recent months, Bordetella pertussis has reappeared after maintaining a low rate for many years. Although pertussis is usually characterized by a favorable course, several factors can contribute to the severity of the disease, such as mixed respiratory infections. In this study, we evaluate B.pertussis cases observed in the pediatric population followed at the Bambino Gesù Children's Hospital and analyzed the potential impact of co-infections in relation to disease severity.

Methods

From January to May 2024, a total of 1,151 children and adolescents (both inpatients and outpatients) were screened for the presence of respiratory pathogens, including B.pertussis, with clinically relevant respiratory symptoms.

Results

Among the 1,151 patients screened, 66 te

SUBMITTER: Scutari R 

PROVIDER: S-EPMC11749163 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature