DepRescribing inapprOpriate Proton Pump InhibiTors (DROPIT): study protocol of a cluster-randomised controlled trial in Swiss primary care.

ABSTRACT:

Objectives

Proton pump inhibitors (PPIs) are widely prescribed medications and commonly used for the treatment of gastric acid-related disorders. Nevertheless, PPIs are often overused leading to potential adverse effects and unnecessary healthcare costs. Deprescribing strategies have emerged to safely reduce or substitute inappropriate PPIs and optimise patient care in an evidence-based manner. This protocol describes a study to evaluate the effectiveness of a PPI deprescribing intervention in comparison to usual care in the Swiss primary care setting.

Design

An open-label, cluster randomised controlled trial.

Setting

Swiss primary care settings.

Participants

Included participants will be adults with inappropriate PPI treatment and will be recruited by general

SUBMITTER: Schulthess-Lisibach AE 

PROVIDER: S-EPMC11749314 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature