Donor hepatitis C status is not associated with an increased risk of acute rejection in kidney transplantation.

ABSTRACT:

Introduction

In renal transplantation, donor hepatitis C virus (HCV) status is crucial to consider when selecting a recipient given the high likelihood of transmission. We analyzed the effect of donor HCV status on post-renal transplant rejection and virologic infectious outcomes using electronic health record data from multiple US health care organizations.

Methods

Using real world data from electronic health records of renal transplant recipients, a propensity score-matched case-control study of one-year renal transplant outcomes was conducted on cohorts of HCV-negative recipients who received an organ from an HCV-positive donor (HCV D+/R-) versus from an HCV-negative donor (HCV D-/R-). Donor HCV positivity was defined as new recipient HCV positivity within 30 days post-tr

SUBMITTER: Johnson JC 

PROVIDER: S-EPMC11749424 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature