Impact of exposure to opioids in pregnancy on offspring developmental outcomes in the preschool years: an umbrella review.

ABSTRACT:

Background

Early child development sets the course for optimal outcomes across life. Increasing numbers of children worldwide are exposed to opioids in pregnancy and frequently live in environments associated with adverse developmental outcomes. Although multiple systematic reviews have been published in this area, they use different exposures and different types of outcomes. This umbrella review aims to bring together these systematic reviews to provide a comprehensive overview of the evidence around the association between prenatal opioid exposure and preschool developmental outcomes.

Methods

PubMed, MedLine, PsycInfo and Google Scholar were searched up to July 2024. Eligible studies were systematic reviews, meta-analyses or scoping reviews exploring prenatal opioid exposu

SUBMITTER: Robertson S 

PROVIDER: S-EPMC11749434 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature