Risk factors for brain metastasis in lung cancer: an umbrella review of systematic reviews and meta-analyses.

ABSTRACT:

Objectives

To conduct an umbrella review to extensively evaluate and summarise the evidence regarding the relationship between risk factors and the occurrence of brain metastasis in lung cancer.

Design

Umbrella review of systematic reviews and meta-analyses.

Data sources

Four databases (PubMed, EMBASE, Web of Science and Cochrane Library) were searched from inception to 10 November 2024.

Eligibility criteria

Systematic reviews and meta-analyses that assessed the relationship between risk factors and brain metastasis in lung cancer were included. Only English language studies were considered.

Data extraction and synthesis

Two authors independently extracted data and assessed the methodological quality and risk of bias of the included studies. Certainty of

SUBMITTER: Wan X 

PROVIDER: S-EPMC11749772 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature