Long-term outcome of oesophageal atresia in adolescence (TransEAsome): a national French cohort study protocol.

ABSTRACT:

Introduction

The TransEAsome project, funded by the Agence Nationale de la Recherche, aims to evaluate the long-term outcomes of patients with oesophageal atresia (OA) between 13 and 14 years old and establish multiomics profiles using data from the world's biggest OA registry.

Methods and analysis

TransEAsome is a national multicentre population-based cohort study recruiting participants from all qualified French centres for OA surgery at birth. The primary objective is to assess the prevalence of gastro-oesophageal reflux disease in adolescence among patients with OA, with several secondary objectives including the identification of risk factors and multiomic profiles from oesophageal biopsies and blood samples collected between 13 and 14 years old, compared

SUBMITTER: Leroy M 

PROVIDER: S-EPMC11749844 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature