An atlas of glucose uptake across the entire human body as measured by the total-body PET/CT scanner: a pilot study.

ABSTRACT: Glucose uptake differs in organs and tissues across the human body. To date, however, there has been no single atlas providing detailed glucose uptake profiles across the entire human body. Therefore, we aimed to generate a detailed profile of glucose uptake across the entire human body using the uEXPLORER positron emission tomography/computed tomography scanner, which offers the opportunity to collect glucose metabolic imaging quickly and simultaneously in all sites of the body. The standardized uptake value normalized by lean body mass (SUL) of 18F-fluorodeoxyglucose was used as a measure of glucose uptake. We developed a fingerprint of glucose uptake reflecting the mean SULs of major organs and parts across the entire human body in 15 healthy-weight and 18 overweight subjects. Using the

SUBMITTER: Lu W 

PROVIDER: S-EPMC11749875 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature