Impact of tiered restrictions in December 2020 on COVID-19 hospitalisations in England: a synthetic control study.

ABSTRACT:

Objectives

To evaluate the effectiveness of localised Tier 3 restrictions, implemented in England in December 2020, on reducing COVID-19 hospitalisations compared with less stringent Tier 2 measures and the variations by neighbourhood deprivation and the prevalence of Alpha (B.1.1.7) variant, the primary variant of concern then, to measure hospital services' burden and inequalities across different communities.

Design

Observational study using a synthetic control method, comparing weekly hospitalisation rates in Tier 3 areas to a synthetic control from Tier 2 areas.

Setting

England between 4 October 2020 and 21 February 2021.

Participants

23 million people under Tier 3 restrictions, compared with a synthetic control group derived from 29 million people under Ti

SUBMITTER: Zhang X 

PROVIDER: S-EPMC11749879 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature