Oral Anticoagulant Initiation in Patients With Kidney Failure on Hemodialysis Newly Diagnosed With Atrial Fibrillation (2007-2020): An Observational Study of Trends and Disparities.

ABSTRACT:

Rationale & objective

Atrial fibrillation (AF) is common in patients with kidney failure on hemodialysis (HD), but few patients receive oral anticoagulant (OAC) treatment. Availability of direct-target OACs starting in 2010 may have induced greater OAC initiation, but this has not been systematically studied.

Study design

Retrospective cohort study.

Setting & participants

Using Medicare fee-for-service billing claims (2006-2020), we identified previously OAC-naïve HD patients newly-diagnosed with AF between January 1, 2007, and October 1, 2020.

Exposures

Calendar year; race/ethnicity.

Outcomes

OAC initiation within 90 days from AF diagnosis (any; specific agent).

Analytical approach

We estimated initiation risk ratios for each calendar year compar

SUBMITTER: Winkelmayer WC 

PROVIDER: S-EPMC11750526 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature