Principal investigator gender and clinical trial success: analysis of over 3000 obstetrics and gynecology trials.

ABSTRACT:

Background

In obstetrics and gynecology (OBGYN) research, gender disparities permeate through leadership, funding, promotion, mentorship, publishing, compensation, and publicity. Few studies have investigated OBGYN clinical trial leadership as it relates to investigator gender. Thus, we undertook an investigation of principal investigator (PI) gender and clinical trial success.

Objective

To characterize United States (US) OBGYN clinical trials by PI gender and analyze the association between PI gender and features of trial success.

Study design

This is a cross-sectional study of all US-based obstetric and gynecologic clinical trials registered on ClinicalTrials.gov (2007-2020). We examined associations between PI gender (ie, led by women, men, or both) and four primar

SUBMITTER: Steinberg JR 

PROVIDER: S-EPMC11750538 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature