Study on gene expression in the liver at various developmental stages of human embryos.

ABSTRACT:

Background

The normal development of the liver during human embryonic stages is critical for the functionality of the adult liver. Despite this, the essential genes, biological processes, and signal pathways that drive liver development in human embryos remain poorly understood.

Methods

In this study, liver samples were collected from human embryos at progressive developmental stages, ranging from 2-month-old to 7-month-old. Highly expressed genes and their associated enrichment processes at various developmental stages of the liver were identified through transcriptomic sequencing.

Results

The findings indicated that genes associated with humoral immune responses and B-cell-mediated immunity were highly expressed during the early developmental stages. Concurrently, n

SUBMITTER: Chen H 

PROVIDER: S-EPMC11751009 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature