Assessment of access and outcomes of kidney transplantation through the reforms of the Swiss organ allocation system.

ABSTRACT:

Introduction

The Swiss allocation system for kidney transplantation has evolved over time to balance medical urgency, immunological compatibility, and waiting time. Since the introduction of the transplantation law in 2007, which imposed organ allocation on a national level, the algorithm has been optimized. Initially based on waiting time, HLA compatibility, and crossmatch performed by cell complement-dependent cytotoxicity techniques, the system moved in 2012 to a score including HLA compatibility, waiting time, anti-HLA antibodies detected by the Luminex^® technology, and a virtual crossmatch. In 2015, the score was optimized to balance the impact of preemptive listing and HLA matching of hyperimmunized recipients.

Methods

We reviewed access to transplants and p

SUBMITTER: Bertacchi M 

PROVIDER: S-EPMC11751015 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature