Dynamics of coagulation proteins upon ICU admission and after one year of recovery from COVID-19: a preliminary study.

ABSTRACT:

Objectives

This study aimed to investigate the association of baseline coagulation proteins with hospitalization variables in COVID-19 patients admitted to ICU, as well as coagulation system changes after one-year post-discharge, taking into account gender-specific bias in the coagulation profile.

Methods

We conducted a prospective longitudinal study on 49 ICU-admitted COVID-19 patients. Proteins were measured using a Luminex 200™. The association between coagulation protein levels and hospitalization variables was carried out by generalized linear models adjusted by the most relevant covariates.

Results

At ICU admission, lower factor XII, antithrombin, and protein C levels were linked to the need for invasive mechanical ventilation (IMV) or its duration (p=0.028; p=0

SUBMITTER: Behar-Lagares R 

PROVIDER: S-EPMC11751041 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature