CT-based scoring system for diagnosing eosinophilic solid and cystic renal cell carcinoma versus clear cell renal cell carcinoma.

ABSTRACT: Eosinophilic solid and cystic renal cell carcinoma (ESC-RCC) is rare and often misdiagnosed as clear cell renal cell carcinoma (ccRCC). Therefore, a CT-based scoring system was developed to improve differential diagnosis. Retrospectively, 25 ESC-RCC and 176 ccRCC cases, were collected. The two groups were matched on a 1:2 basis using the propensity-score-matching (PSM) method, with matching factors including sex and age. Finally, 25 ESC-RCC and 50 ccRCC cases were included and randomly divided into a training cohort (52 cases) and a validation cohort (23 cases). Logistic regression identified significant factors, constructed the primary model, and assigned weights for the scoring model. Diagnostic performance was compared using receiver operating characteristic curves, dividing points into

SUBMITTER: Fu S 

PROVIDER: S-EPMC11751170 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature