Treatment with Autologous Adipose-derived Regenerative Cells for Peyronie's Disease in Men: The Straight @head Pilot Study.

ABSTRACT:

Background and objective

We evaluated the effectiveness of injecting autologous adipose-derived regenerative cells (ADRCs) into plaque in men with chronic Peyronie's disease (PD).

Methods

This pilot safety study recruited 22 Danish men with chronic PD from an outpatient clinic. Patients received one bolus of ADRCs injected into plaque, with follow-ups at 1, 3, 6, and 12 mo. The primary endpoint was a reduction in penile curvature. Secondary endpoints were serious adverse events in relation to treatment, and patient-reported results for improvements, distress, and unhappiness related to PD.

Key findings and limitations

There was no significant difference in curvature after treatment. However, the participants reported subjective improvements, less distress, and a decre

SUBMITTER: Wiborg MH 

PROVIDER: S-EPMC11751568 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature