Development of a Novel Clinical Classification for Radiation-induced Cystitis: The Portuguese Navy Radiation-induced Cystitis (PNRC) Scale.

ABSTRACT:

Background and objective

Radiation-induced cystitis (RIC) is an important consequence of pelvic radiotherapy that can cause high morbidity and, in extreme cases, mortality. The lack of a widely accepted classification system makes it difficult to compare treatment regimens. Our aim was to develop a new classification system covering the RIC spectrum to improve treatment comparisons and accurate incidence estimates for systematic use in clinical and research settings.

Methods

A three-phase project was planned. Phase 1 involved a literature review and development of the Portuguese Navy Radiation-induced Cystitis (PNRC) scale. In phase 2 the scale was applied to 20 clinical cases. Phase 3 involved assessment of the applicability, relevance, inter-rater reliability, and usabilit

SUBMITTER: Ribeiro de Oliveira T 

PROVIDER: S-EPMC11751575 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature