Noninvasive Oral Hyperspectral Imaging-Driven Digital Diagnosis of Heart Failure With Preserved Ejection Fraction: Model Development and Validation Study.

ABSTRACT:

Background

Oral microenvironmental disorders are associated with an increased risk of heart failure with preserved ejection fraction (HFpEF). Hyperspectral imaging (HSI) technology enables the detection of substances that are visually indistinguishable to the human eye, providing a noninvasive approach with extensive applications in medical diagnostics.

Objective

The objective of this study is to develop and validate a digital, noninvasive oral diagnostic model for patients with HFpEF using HSI combined with various machine learning algorithms.

Methods

Between April 2023 and August 2023, a total of 140 patients were recruited from Renmin Hospital of Wuhan University to serve as the training and internal testing groups for this study. Subsequently, from August 2024 to

SUBMITTER: Yang X 

PROVIDER: S-EPMC11751651 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature