External Validation of a 5-Factor Risk Model for Breast Cancer-Related Lymphedema.

ABSTRACT:

Importance

Secondary lymphedema is a common, harmful side effect of breast cancer treatment. Robust risk models that are externally validated are needed to facilitate clinical translation. A published risk model used 5 accessible clinical factors to predict the development of breast cancer-related lymphedema; this model included a patient's mammographic breast density as a novel predictive factor.

Objective

To investigate the external validity of a previously reported 5-factor model by applying it to an independent cohort of patients with breast cancer.

Design, setting, and participants

This prognostic study collected data on a longitudinal cohort of patients with predominantly early-stage breast cancer treated with curative intent at the Princess Margaret Cancer Cent

SUBMITTER: Lin C 

PROVIDER: S-EPMC11751742 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature