Protocol for the development of a global core outcome set for the surgical treatment of differentiated thyroid cancer: a literature review and international Delphi survey.

ABSTRACT:

Introduction

There is a lack of consensus on the optimal surgical strategy for differentiated thyroid cancer (DTC), partly due to inconsistent reporting of outcomes. This limits the ability to compare study results, hindering the ability to draw conclusions regarding novel treatment strategies. The development of a core outcome set (COS) reduces heterogeneity in the selection and reporting of clinical trial outcomes. Currently, there is no COS for the surgical treatment of DTC. We aim to reach a global consensus among patients and physicians on the COS for the surgical treatment for patients with DTC of all ages.

Methods and analysis

The DTC-COS development will consist of three phases: first, an extensive literature review will be performed to identify reported outcomes in

SUBMITTER: van de Berg DJ 

PROVIDER: S-EPMC11751832 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature