Safe Implementation of Treatments in Stroke: a study on intravenous thrombolysis in patients over 80 years of age with acute ischaemic stroke.

ABSTRACT:

Objectives

To investigate the safety and efficacy outcomes of intravenous thrombolysis (IVT) in patients aged >80 years with acute ischaemic stroke (AIS) after IVT was approved in this patient population in several European and non-European countries during 2018-2019.

Design

This is an observational registry study using prospectively collected data from the Safe Implementation of Treatment in Stroke (SITS) registry. Comparisons will be performed between patients treated post-approval (July 2018 to December 2021) period with those treated pre-approval (June 2015 to June 2018) period using propensity score matching (PSM).

Setting

This is a multicentre international study in hospitals treating AIS with IVT.

Participants

Patients aged >80 years who otherwise follow

SUBMITTER: Matusevicius M 

PROVIDER: S-EPMC11751842 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature