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Diffusion tensor imaging in peroneal neuropathy: a prospective, single-centre study.


ABSTRACT:

Objective

Diffusion tensor imaging (DTI) showed promising results in diagnosing upper limb neuropathies, but its value in patients with foot drop due to peroneal neuropathy has not yet been investigated. We aim to establish reference values for DTI metrics of the healthy peroneal nerve and to evaluate differences in DTI metrics between patients and healthy controls.

Methods

Diffusion-weighted images (DWI) from 22 pathological nerves, 14 asymptomatic patients' nerves and 65 healthy peroneal nerves were processed for quantitative assessment of fractional anisotropy (FA), radial diffusivity (RD), axial diffusivity and mean diffusivity. Clinical baseline and follow-up data were prospectively collected for all patients.

Results

Mean patient FA values (0.40, SD 0.08) were s

SUBMITTER: Oosterbos C 

PROVIDER: S-EPMC11751924 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature