Maternal characteristics impact the relationship between fetal sex and superimposed preeclampsia.

ABSTRACT:

Objectives

Associations between female fetal sex and preeclampsia occurring preterm have been reported but data is inconsistent across populations. We explored if the relationship between fetal sex and various hypertensive disorders of pregnancy (HDP) is modified by maternal characteristics.

Study design

We conducted a retrospective cohort study analyzing data from 43,737 singleton pregnancies. A modified Poisson regression model with robust error variance was used to calculate relative risk (RR) and 95% confidence intervals (CI) for the association between female fetal sex and HDP.

Main outcome measures

Models were adjusted for maternal age, smoking, body mass index, and gravidity. Relative excess risk due to interaction examined interaction between maternal characte

SUBMITTER: Noah AI 

PROVIDER: S-EPMC11751948 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature