EXamining the feasibility of exerCisE to manage symptoms of Lupus (EXCEL): a protocol for a randomised controlled pilot study.

ABSTRACT:

Introduction

SLE is a chronic autoimmune disease that results in sustained hyperactivation of innate and adaptive immune cells and widespread inflammatory damage. Regular exercise reduces SLE symptoms including fatigue and joint pain and improves patient quality of life. However, most individuals with SLE are not sufficiently active to achieve these benefits, and guidance on the optimal approach to exercise is limited. EXCEL will examine the feasibility of conducting a large-scale randomised controlled trial comparing the effects of a remotely monitored, home-based, exercise programme with standard of care for individuals with SLE.

Methods and analysis

30 females with SLE will be recruited, and those randomised into Exercise (SLE-Ex) will codesign a progressive training plan

SUBMITTER: Quickfall M 

PROVIDER: S-EPMC11751982 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature