Laser interstitial thermal therapy in the management of bottom-of-sulcus dysplasia-related epilepsy.

ABSTRACT:

Objective

This study assessed the efficacy and safety of magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) versus open surgery (OS) for the treatment of patients with bottom-of-sulcus dysplasia (BOSD)-related epilepsy.

Methods

Twenty-two patients underwent MRgLITT, while 39 underwent OS. Postoperative seizure-free rates were analyzed using Kaplan-Meier curves. The removal ratio, which represents the extent of damage, was calculated based on preoperative lesion volume and postoperative removal volume. Other outcomes, including adverse events, operative time, and hospital stay, were also compared.

Results

Kaplan-Meier curves indicated the seizure-free rates were comparable between the MRgLITT group (90.9%, 26.5 [23.0, 35.1] months) and OS group (89.

SUBMITTER: Yang B 

PROVIDER: S-EPMC11752102 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature