Resistify: A Novel NLR Classifier That Reveals Helitron-Associated NLR Expansion in Solanaceae.

ABSTRACT: Nucleotide-binding domain leucine-rich repeat (NLR) proteins are a key component of the plant innate immune system. In plant genomes, NLRs exhibit considerable presence/absence variation and sequence diversity. Recent advances in sequencing technologies have made the generation of high-quality novel plant genome assemblies considerably more straightforward. Accurately identifying NLRs from these genomes is a prerequisite for improving our understanding of NLRs and identifying novel sources of disease resistance. While several tools have been developed to predict NLRs, they are hampered by low accuracy, speed, and availability. Here, the NLR annotation tool Resistify is presented. Resistify is an easy-to-use, rapid, and accurate tool to identify and classify NLRs from protein sequences. App

SUBMITTER: Smith M 

PROVIDER: S-EPMC11752215 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature