Ligand-Induced Activation of Single-Atom Palladium Heterogeneous Catalysts for Cross-Coupling Reactions.

ABSTRACT: Single-atom heterogeneous catalysts (SACs) are potential, recoverable alternatives to soluble organometallic complexes for cross-coupling reactions in fine-chemical synthesis. When developing SACs for these applications, it is often expected that the need for ligands, which are essential for organometallic catalysts, can be bypassed. Contrary to that, ligands remain almost always required for palladium atoms stabilized on commonly used functionalized carbon and carbon nitride supports, as the catalysts otherwise show limited activity. Despite this, ligand optimization has received little attention, and their role in activating SACs is poorly understood. Here, we explore the impact of structurally diverse phosphine ligands on the performance of nitrogen-doped carbon supported single-atoms (

SUBMITTER: Poier D 

PROVIDER: S-EPMC11752494 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature