Burden of pertussis in infants in the Eastern Mediterranean Region and the impact of maternal vaccination: a systematic review.

ABSTRACT:

Background

Despite vaccine availability, Pertussis remains a global public health challenge, especially among infants. The Eastern Mediterranean Region (EMR) presents a diverse epidemiological landscape with varying vaccination coverages and healthcare infrastructures. This systematic review aimed to assess the burden of pertussis in infants < 1 year of age in the EMR and evaluate the use and impact of pertussis vaccination during pregnancy.

Methods

Following PRISMA guidelines, we conducted a systematic search of Scopus, Embase, CINAHL Ultimate, and PubMed from inception until April 30, 2024. Studies included reported on pertussis burden in infants or maternal vaccination. Data extraction and quality assessment were performed in duplicate, focusing on incidence, age distribu

SUBMITTER: Saad RK 

PROVIDER: S-EPMC11752665 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature